Anion Gap... or 'strong ion difference' represents the relative amount of anions and cations required for electrical neutrality and pH balance in the body. Anions Cl-, SO4=, and HPO4+ are balanced with cations primarily sodium Na+ and some potassium K+, magnesium Mg++, and Calcium Ca++ .  The SID (strong ion difference) represents the combined concentration of protein anions and bicarbonate - with bicarbonate HCO3- playing the most significant role because it can be adjusted by the kidneys.

Because there's no proteins or cells of any kind in cerebral spinal fluid, electrolytes must be present to create a strong ion difference and move bicarbonate into the CSF to maintain pH during exercise. Typically in exercise, as carbon dioxide causes an increase in H+ in the cerebral spinal fluid there is insufficient bicarbonate due to slow process of kidney production. The increase in K+ also slows the removal of H+,and electrolytes are used up as strong ion pumps attempt to reestablish the SID.

Body'Fit [pH Fitness uses several means to the achieve the anion gap for a strong ion difference.  Maintaining aerobic metabolism normalizes the R ratio of CO2 to O2. *No relative increase in H+ or K+ occurs. Any demand for ions is met with techniques that enhance the direct absorption of gases from the atmosphere, equitable distribution throughout the body, and acceleration of renal reabsorption of bicarbonate by providing additional circulation to the abdominal cavity.

*Incidently since the usual acidic exercise pH is prevented during Body'Fit pH Fitness, the bones are not robbed of minerals as they normally are under stress of exercise. There's reason enough to augment with Body'Fit pH Fitness. Dr. Nancy Appleton argues this point in her book "Healthy Bones: What You Should Know About Osteoporosis". She says this is the cause that has been overlooked: body chemistry.